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Clinicians and healers have been utilizing and prescribing a wide range of weight loss regimens for centuries. As early as BCE, the dangers of obesity started to be recognized. Indian physician Sushruta wrote of a disease he called madhumeha. During this time, the earliest anti-obesity recommendations on diet and exercise were born and included the use of the following: emetics hellebore plants, honey , cathartics bindweed, Cnidian berry , and laxatives donkey milk, wild parsley, and dodder of thyme.

In the late s, weight loss regimens began to modernize.

Dr. Ronald Kohn, MD

In , British physician Nathaniel Edward Yorke-Davies began documenting weight loss in patients with obesity after he had given them desiccated thyroid. Following his example, other clinicians began to experiment with desiccated thyroid, combining it with strychnine and other hazardous drugs in an attempt to enhance its effect on weight loss. A little over a century later, the s brought with it newly discovered anorectic effects of amphetamine, which generated tremendous interest among physicians and pharmaceutical firms who sought to capitalize on its use for weight loss.

Since the s, the numbers of weight loss supplements have only increased. To name a few; diethylproprion , amphetamine , 2,4 dinitrophenol s , fenfluramine and dexfenfluramine , sibutramine — , orlistat , and beta-methlyphenethylamine As of , there are now over 10 FDA-approved and regulated anti-obesity medications on the market. Fortunately for consumers, 21st century physician-prescribed anti-obesity medications are vetted through rigorous clinical trials and FDA regulatory measures.

While the role of functional foods, vitamins, minerals, and other supplementation should always be considered when discussing weight loss options, it is important as a provider to be familiar with and understand the mechanisms and efficacy of such supplements before promoting them for weight loss. Garcinea cambogia. Claim: Promotes satiety, prevents fat production, controls blood sugar and cholesterol levels.

Active ingredient: Hydroxycitric acid HCA , thought to block enzyme citrate lyase and boost serotonin levels. Clinical results: In a literature search from to , there were only eight randomized, double-blind, placebo-controlled trials that sought to evaluate the effects of garcinea cambogia on body weight in patients with obesity. In a further analysis of those eight studies, a borderline statistically significant mean difference in weight loss favoring HCA over placebo use was found mean difference: —0.

However, this result was not statistically significant when run through a sensitivity analysis. Summary: In lieu of poor data collection, variance in populations studied, and lack of long-term research, it is difficult to conclude whether this supplement has any real, long-term effect on weight loss. Conjugated linoleic acid CLA. Claim: Fat loss, weight loss, glycemic control. Active Ingredient: A naturally occurring group of positional and geometric linoleic acid isomers cis-9, trans and cis, trans Clinical results: A study published in the International Journal of Obesity found that during a one-year study where test subjects received 3.

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One of the three with reported significance noted that CLA t11, c9 had no significant effect when given in a low dose, but decreased body fat when the dose was increased. Green coffee bean extract. But, at the age of 25, he decided to put his degree aside and start his own construction business.


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The year-old Pepper Pike resident built a successful company as a commercial real estate developer. And, as he flipped his career, his life began to flop. Through the years, his life habits caused him to gain weight and develop health problems.

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His physician advised him to make modifications like decreasing his sodium intake, eating healthy foods and exercising. He made a half-hearted attempt. He went to the emergency room and ended up in the hospital for a few days.

The Best Ways to Lose Half Your Body Weight

After having a hip replacement in October , he developed pulmonary arterial hypertension — essentially high blood pressure in the lungs that causes the arteries to become narrow or blocked. This caused shortness of breath and difficulty in walking long distances so Gary used a wheelchair to get around. With all of these medical issues popping up, Gary was determined to get his health back. Ronald J. Kohn is a family medicine specialist and weight loss physician. Kohn and his staff.

Having a quality primary care medical provider is the key to staying healthy, preventing disease, and living the most enjoyable life possible. Kohn can identify conditions that may interfere with your quality of life, such as heart disease , diabetes and sleep apnea , and offer medications and recommendations for their management. With Dr.

Gary Kohn: Weight Loss Patient Story | Cleveland Clinic

Kohn as your doctor, you can expect specialized attention and customized treatment plans made especially for you. In addition to physical examinations , wellness exams and weight loss counseling , Dr. Reach your goals with Dr.